Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10904448 | 0.77 | TP53 (0.45) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL8429953 | 0.76 | PDE4A (0.48) | SMN1; SMN2LMNAPDE4APDE4BPDE4C | |
| SCHEMBL28129195 | 0.76 | PDE4A (0.40) | NPC1RAB9ASMN1; SMN2PDE4APDE4B | |
| SCHEMBL8830212 | 0.76 | CYP3A4 (0.54) | NPC1RAB9ASMN1; SMN2PDE4APDE4B | |
| SCHEMBL10902250 | 0.75 | MAPT (0.43) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL28416982 | 0.75 | PDE4A (0.50) | NPC1RAB9ASMN1; SMN2LMNAPDE4A | |
| SCHEMBL4269788 | 0.74 | NR2E1 (0.47) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL11375358 | 0.73 | PDE4A (0.51) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL239663 | 0.73 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL10902023 | 0.73 | KCNH2 (0.55) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102753532-B | Process for preparation of medetomidine | TECH AB I | 2015-05-13 | — | — | CN | disclosed |