Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992922 | 0.80 | MEN1 (0.48) | CYP1A2KDM4EMEN1KMT2A | |
| SCHEMBL5456634 | 0.80 | CYP1A2 (0.67) | CYP1A2KDM4EMAPTTDP1LMNA | |
| SCHEMBL15415316 | 0.79 | KDM4E (0.53) | KDM4EMAPTTDP1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL3805296 | 0.79 | CYP1A2 (0.65) | CYP1A2KDM4EMAPTTDP1LMNA | |
| SCHEMBL3720399 | 0.79 | KDM4E (0.59) | CYP1A2KDM4EMAPTTDP1LMNA | |
| Hydrochloric Acid SCHEMBL3712126 | 0.77 | KDM4E (0.57) | CYP1A2KDM4EMAPTTDP1LMNA | |
| SCHEMBL8372588 | 0.77 | GSK3A (0.40) | KDM4EMAPTTDP1LMNAMEN1 | |
| SCHEMBL16361004 | 0.76 | CCR1 (0.51) | CYP1A2KDM4EMAPTTDP1LMNA | |
| SCHEMBL9862809 | 0.76 | MAPT (0.46) | CYP1A2KDM4EMAPTTDP1LMNA | |
| SCHEMBL10157046 | 0.75 | KDM4E (0.68) | CYP1A2KDM4EMAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507913-A | Antiproliferative benzo[b]azepin-2-ones | HOFFMANN LA ROCHE | 2015-04-08 | — | — | CN | disclosed |