Dibenzyl Disulfide

Dibenzyl Disulfide

SCHEMBL28006296

NC(N)=O.c1ccc(CSSCc2ccccc2)cc1

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.56
NOS1 P29475 2/20 0.56
NOS3 P29474 1/20 0.56
NOS2 P35228 1/20 0.56
CYP2C19 P33261 1/20 0.50
PLA2G10 O15496 1/20 0.47
PLA2G2A P14555 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
AKR1B1 P15121 1/20 0.46
PTPRC P08575 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
GAA P10253 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
EPHX1 P07099 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.43
POLB P06746 1/20 0.43
ALPI P09923 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzyl Disulfide SCHEMBL27853226 0.98 IDO1 (0.54) IDO1NOS1NOS3NOS2CYP2C19
Dibenzyl Disulfide SCHEMBL27966611 0.95 IDO1 (0.56) IDO1NOS1NOS3NOS2CYP2C19
Dibenzyl Disulfide SCHEMBL31120422 0.89 IDO1 (0.50) IDO1NOS1NOS3NOS2CYP2C19
Urea SCHEMBL27623582 0.86 CYP2C19 (0.61) IDO1NOS1NOS3NOS2CYP2C19
Dibenzyl Disulfide SCHEMBL160895 0.84 HSD17B10 (0.52) IDO1NOS1NOS3NOS2CYP2C19
Dibenzyl Disulfide SCHEMBL16332737 0.84 HSD17B10 (0.52) IDO1NOS1NOS3NOS2CYP2C19
Dibenzyl Disulfide SCHEMBL27883972 0.83 CYP2C19 (0.44) IDO1NOS1NOS3NOS2CYP2C19
Dibenzyl Disulfide SCHEMBL27512197 0.82 IDO1 (0.50) IDO1NOS1NOS3NOS2CYP2C19
Dibenzyl Disulfide SCHEMBL29247901 0.82 CYP2C19 (0.52) IDO1NOS1NOS3NOS2CYP2C19
SCHEMBL5597374 0.82 CYP2C19 (0.52) IDO1NOS1NOS3NOS2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104370784-B Naphthenic-base zinc sulfide compound and preparation method thereof 北京彤程创展科技有限公司 2017-02-22 CN disclosed
CN-104370784-A Naphthenic-base zinc sulfide compound and preparation method thereof BEIJING RED AVENUE INNOVA CO LTD 2015-02-25 CN disclosed