Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.82 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.73 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.72 |
| ▸ | SRC | P12931 | 2/20 | 0.72 |
| ▸ | FYN | P06241 | 1/20 | 0.72 |
| ▸ | BLK | P51451 | 1/20 | 0.72 |
| ▸ | BMX | P51813 | 1/20 | 0.72 |
| ▸ | JAK3 | P52333 | 1/20 | 0.72 |
| ▸ | BTK | Q06187 | 1/20 | 0.72 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585935 | 0.90 | EGFR (1.00) | EGFRERBB2ERBB4SRCFYN | |
| SCHEMBL29918398 | 0.90 | EGFR (1.00) | EGFRERBB2ERBB4SRCFYN | |
| SCHEMBL2944459 | 0.90 | EGFR (1.00) | EGFRERBB2ERBB4SRCFYN | |
| SCHEMBL8781957 | 0.90 | EGFR (0.88) | EGFRERBB2ERBB4ABCG2 | |
| SCHEMBL15782168 | 0.89 | EGFR (0.82) | EGFRERBB2ERBB4SRCFYN | |
| SCHEMBL27562082 | 0.88 | EGFR (0.83) | EGFRERBB2ERBB4SRCFYN | |
| SCHEMBL3467130 | 0.88 | EGFR (0.84) | EGFRERBB2ERBB4 | |
| SCHEMBL27921974 | 0.88 | SRC (0.83) | EGFRERBB2ERBB4SRCFYN | |
| SCHEMBL4586021 | 0.87 | EGFR (1.00) | EGFRERBB2ERBB4ABCG2 | |
| SCHEMBL27572603 | 0.87 | EGFR (0.79) | EGFRERBB2ERBB4SRCFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850397-B | Multi-target antitumor compounds and preparation method and application thereof | UNIV BEIJING | 2015-02-18 | — | — | CN | disclosed |