Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12312297 | 0.91 | MAPT (0.55) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL17265647 | 0.89 | CYP1A2 (0.51) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL16640693 | 0.87 | GAA (0.58) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL18447001 | 0.86 | GAA (0.41) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL29508973 | 0.85 | MAPT (0.58) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL1912036 | 0.85 | MAPT (0.58) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL17265652 | 0.84 | GAA (0.49) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL28668816 | 0.84 | GAA (0.54) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL1781835 | 0.80 | MAPT (0.52) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL17264112 | 0.80 | CYP1A2 (0.45) | GAATSHRRAD52CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102260187-B | Substituted carbamyl cyclohexane carboxylic acid compound as well as preparation method and application thereof | INST MATERIA MEDICA CAMS | 2015-04-15 | — | — | CN | disclosed |