Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25610863 | 0.87 | TPMT (0.65) | TPMTKDM4ETDP1HCAR1GPR35 | |
| SCHEMBL3097749 | 0.84 | TPMT (0.56) | TPMTKDM4ETDP1MEN1KMT2A | |
| Fluoride SCHEMBL11641082 | 0.82 | TPMT (0.54) | TPMTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL16652911 | 0.81 | KDM4E (0.44) | TPMTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL25604523 | 0.81 | TPMT (0.58) | TPMTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL1568514 | 0.78 | KDM4E (0.45) | TPMTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL71249 | 0.78 | TPMT (0.50) | TPMTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL1233792 | 0.78 | TPMT (0.54) | TPMTKDM4ETDP1HCAR1GPR35 | |
| SCHEMBL29528375 | 0.78 | TPMT (0.54) | TPMTKDM4ETDP1KMT2AHCAR1 | |
| SCHEMBL22468505 | 0.78 | TPMT (0.54) | TPMTHCAR1GPR35CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001320-A | 1-alkyl-6-oxo-1, 6-dihydropyridin-3-yl compounds and their use | 阿斯利康(瑞典)有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106414413-A | Sulfonamide derivatives and pharmaceutical use thereof | EA制药株式会社 | 2017-02-15 | — | — | CN | disclosed |
| CN-106061963-A | Heterocyclic modulators of lipid synthesis and combinations thereof | 3-V生物科学股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-104507928-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-103415507-B | As the 3-amino-pyridine class of GPBAR1 agonist | HOFFMAN-LA ROCHE LTD. (CH) | 2016-03-02 | — | — | CN | disclosed |
| CN-104507928-A | Heterocyclic modulators of lipid synthesis | 3 V BIOSCIENCES INC | 2015-04-08 | — | — | CN | disclosed |