Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 known ✓ | P29475 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28686 | 0.90 | MAPT (0.54) | POLBALDH1A1MAPTMAOBNOS1 | |
| SCHEMBL30597526 | 0.90 | MAPT (0.54) | POLBALDH1A1MAPTMAOBNOS1 | |
| Propionic Acid SCHEMBL27602614 | 0.90 | POLB (0.45) | POLBMEN1ALDH1A1PKMNPY1R | |
| Ammonia Solution, Strong SCHEMBL28394313 | 0.89 | MAPT (0.53) | POLBALDH1A1MAPTMAOBNOS1 | |
| Methane SCHEMBL27929615 | 0.89 | MAPT (0.53) | POLBALDH1A1MAPTMAOBNOS1 | |
| Acrylic Acid SCHEMBL29048066 | 0.87 | MAPT (0.43) | POLBMEN1ALDH1A1PKMNPY1R | |
| Phosphoric Acid SCHEMBL594274 | 0.86 | MAPT (0.47) | POLBMAPTMAOBNOS1HRH4 | |
| SCHEMBL21359704 | 0.84 | MAPT (0.46) | POLBALDH1A1MAPTMAOBNOS1 | |
| Phosphoramidic Acid SCHEMBL312721 | 0.83 | MAPT (0.45) | POLBALDH1A1MAPTMAOBNOS1 | |
| Pyridine SCHEMBL28517154 | 0.82 | MAPT (0.48) | POLBMAPTMAOBNOS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447492-A | Method for synthesizing 5-nitro indoleacetic acid | UNIV CHANGZHOU | 2015-03-25 | — | — | CN | disclosed |