Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019911 | 0.88 | PDE10A (0.45) | KMT2AMEN1POLBPABPC1 | |
| SCHEMBL7017481 | 0.84 | KMT2A (0.40) | KMT2AMEN1POLBPABPC1TP53 | |
| SCHEMBL7015218 | 0.82 | MEN1 (0.39) | KMT2AMEN1POLBPABPC1TP53 | |
| SCHEMBL6386347 | 0.82 | MEN1 (0.39) | KMT2AMEN1POLBPABPC1TP53 | |
| SCHEMBL7016110 | 0.82 | — | — | |
| SCHEMBL28008635 | 0.81 | MEN1 (0.44) | KMT2AMEN1POLBPABPC1TP53 | |
| SCHEMBL27600241 | 0.80 | POLB (0.48) | KMT2AMEN1POLBPABPC1BLM | |
| SCHEMBL7018959 | 0.79 | MEN1 (0.43) | KMT2AMEN1POLBPABPC1TP53 | |
| SCHEMBL7097040 | 0.79 | ESR1 (0.40) | KMT2AMEN1POLBPABPC1TP53 | |
| SCHEMBL6426223 | 0.79 | PSEN1 (0.45) | KMT2AMEN1SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101967146-B | Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents | RAQUALIA PHARMA INC | 2015-04-08 | — | — | CN | disclosed |