SCHEMBL28009265

SCHEMBL28009265

Clc1ccnc(Cl)c1Cl.O=CCl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34
DAO P14920 1/20 0.34
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
AXL P30530 1/20 0.32
PRKCI P41743 1/20 0.32
CCR4 P51679 1/20 0.31
NFE2L2 Q16236 2/20 0.31
HSD17B10 Q99714 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
APEX1 P27695 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL27730053 0.89 SMN1; SMN2 (0.35) ALDH1A1TDP1MEN1KMT2ACCR1
SCHEMBL170627 0.88
SCHEMBL31609474 0.88
Ammonia Solution, Strong SCHEMBL28110189 0.85 AXL (0.37) TDP1DAOLMNASMN1; SMN2AXL
Fluoride SCHEMBL28977564 0.85 AXL (0.37) TDP1DAOLMNASMN1; SMN2AXL
SCHEMBL27878648 0.85 AXL (0.37) TDP1DAOLMNASMN1; SMN2AXL
SCHEMBL29727505 0.85 AXL (0.37) TDP1DAOLMNASMN1; SMN2AXL
Bromide SCHEMBL9034195 0.85 AXL (0.37) TDP1DAOLMNASMN1; SMN2AXL
SCHEMBL28734915 0.85 AXL (0.37) ALDH1A1TDP1MEN1KMT2ADAO
SCHEMBL27603877 0.85 AXL (0.37) TDP1DAOLMNASMN1; SMN2AXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104583183-A Fluoropicolinoyl fluorides and processes for their preparation DOW AGROSCIENCES LLC 2015-04-29 CN disclosed