Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL30492946 | 0.89 | HCAR2 (0.45) | HCAR2DAOGAALMNAL3MBTL1 | |
| Boric Acid SCHEMBL17848565 | 0.89 | HCAR2 (0.45) | HCAR2DAOGAALMNAL3MBTL1 | |
| SCHEMBL1503 | 0.80 | — | — | |
| SCHEMBL30404482 | 0.78 | — | — | |
| SCHEMBL30802139 | 0.78 | — | — | |
| SCHEMBL29150915 | 0.78 | — | — | |
| SCHEMBL28959328 | 0.78 | HCAR2 (0.44) | HCAR2DAOGAALMNAL3MBTL1 | |
| Potassium SCHEMBL30471622 | 0.78 | — | — | |
| SCHEMBL28852463 | 0.78 | HCAR2 (0.44) | HCAR2DAOGAALMNAL3MBTL1 | |
| SCHEMBL10661053 | 0.75 | HCAR2 (0.43) | HCAR2DAOGAALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540828-B | As the substituted pyrazoloquinazolone and pyrrolo- quinazolinone of the allosteric modulators of II group metabotropic glutamate receptors | 多曼治疗学公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-104540828-A | Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group ii metabotropic glutamate receptors | DOMAIN THERAPEUTICS | 2015-04-22 | — | — | CN | disclosed |