SCHEMBL28010

SCHEMBL28010

FC(F)CI

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30094371 0.74
SCHEMBL1040173 0.74
SCHEMBL17947819 0.70
SCHEMBL7515078 0.70
SCHEMBL6151665 0.70
SCHEMBL10840514 0.70
SCHEMBL3683899 0.70
SCHEMBL8271296 0.67
SCHEMBL9985 0.67
SCHEMBL23285 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2013 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192249-A Preparation method of difluoromethyl building block (1R, 3R) -3- ((tert-butoxycarbonyl) amino) -1- (2, 2-difluoroethyl) cyclopentane-1-methyl formate 无锡捷化医药科技有限公司 2025-06-24 CN claimed
CN-120137738-A Compositions comprising iodofluorocarbons 阿科玛法国公司 2025-06-13 CN claimed
CN-119977753-A Process for producing iodofluorocarbon compounds 阿科玛法国公司 2025-05-13 CN claimed
CN-119954594-A Process for producing iodofluorocarbon compounds 阿科玛法国公司 2025-05-09 CN claimed
CN-119954592-A Process for producing iodofluorocarbon compounds 阿科玛法国公司 2025-05-09 CN claimed
CN-118976524-A Chlorine-defect-containing carbon catalyst and preparation method and application thereof 浙江师范大学 2024-11-19 CN claimed
WO-2024111308-A1 COMPOSITION CONTAINING FLUOROIODOALKANE 東ソー株式会社 2024-05-30 WO claimed
US-20230114828-A1 COMPOSITION COMPRISING AN IODOFLUOROCARBON COMPOUND ARKEMA FRANCE (FR) 2023-04-13 US claimed
US-20230075839-A1 METHOD FOR PRODUCING AN IODOFLUOROALKANE COMPOUND ARKEMA FRANCE (FR) 2023-03-09 US claimed
EP-4107140-A1 METHOD FOR PRODUCING AN IODOFLUOROALKANE COMPOUND ARKEMA FRANCE (FR) 2022-12-28 EP claimed
CN-114956954-A Preparation method of 1,1-difluoro-2-iodoethane 扬州市普林斯医药科技有限公司 2022-08-30 CN claimed
WO-2020053196-A1 METHOD FOR THE BIOCATALYTIC ALKYLATION OF A SUBSTRATE UNIVERSITÄT BASEL (CH) 2020-03-19 WO claimed
CN-110746268-A Fluoroethyl substituted two-dimensional layered germanium and preparation method thereof 天津大学 2020-02-04 CN claimed
CN-108069821-A A kind of difluoroethanol synthesis technology 西安近代化学研究所 2018-05-25 CN claimed
EP-4746965-A1 BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-4746963-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
CN-122080086-A Diimine catalyst, preparation method and application thereof 2026-05-26 CN disclosed
WO-2003010211-A1 PROCESS FOR THE POLYMERIZATION OF ETHYLENE AND INTERPOLYMERS THEREOF EASTMAN CHEMICAL COMPANY (US) 2003-02-06 WO disclosed
US-20020007024-A1 Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst WESTLAKE LONGVIEW CORPORATION 2002-01-17 US disclosed
US-5075494-A Process for the preparation of α-fluoroacrylic acid derivatives and new 1,1-difluoro-2-halogenoethyl (halogeno) methyl ketones BAYER AKTIENGESELLSCHAFT (DE) 1991-12-24 US disclosed