Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515777 | 0.94 | CYP3A4 (0.69) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL2520487 | 0.94 | CYP3A4 (0.69) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL17887253 | 0.93 | LPAR3 (0.53) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL17164135 | 0.92 | CYP3A4 (0.62) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL12914745 | 0.90 | CYP3A4 (0.63) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL14584196 | 0.90 | TSHR (0.45) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL20466177 | 0.88 | TSHR (0.45) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| Ammonia Solution, Strong SCHEMBL31087396 | 0.88 | CYP3A4 (0.61) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL75907 | 0.88 | CYP3A4 (0.56) | CYP3A4TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL29093875 | 0.87 | TSHR (0.60) | CYP3A4TSHRLPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100201939-A1 | PLASTIC LENS AND METHOD OF MANUFACTURING THE SAME | HOYA CORPORATION (JP) | 2010-08-12 | — | — | US | disclosed |
| EP-2172792-A1 | PLASTIC LENS AND METHOD OF MANUFACTURING THE SAME | Hoya Corporation (JP) | 2010-04-07 | — | — | EP | disclosed |