Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825637 | 0.83 | GSK3B (0.77) | GSK3BMAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL28010769 | 0.83 | GSK3B (0.59) | GSK3BMAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL2672578 | 0.80 | HSD17B10 (0.45) | GSK3BMAPTTP53POLBIDO1 | |
| SCHEMBL4999162 | 0.77 | MAPT (0.49) | GSK3BMAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL18025747 | 0.75 | GSK3B (0.73) | GSK3BMAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL28649392 | 0.75 | GSK3B (0.73) | GSK3BMAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL7372759 | 0.75 | GSK3B (0.73) | GSK3BMAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL8806656 | 0.75 | GSK3B (0.72) | GSK3BMAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL27915346 | 0.73 | TAAR1 (0.43) | IDO1 | |
| SCHEMBL6744208 | 0.73 | GSK3B (0.58) | GSK3BMAPTKDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529894-B | Quinolinone derivative and preparation method thereof | 成都丽凯手性技术有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104529830-A | Novel urea type compound preparation method | CHENGDU LIKAI CHIRAL TECHNOLOGY CO LTD | 2015-04-22 | — | — | CN | disclosed |
| CN-104529894-A | Quinolinone derivative and preparation method thereof | CHENGDU LIKAI CHIRAL TECHNOLOGY CO LTD | 2015-04-22 | — | — | CN | disclosed |