Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509431 | 0.77 | — | — | |
| SCHEMBL295774 | 0.77 | — | — | |
| SCHEMBL11509433 | 0.77 | GAA (0.54) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL10676884 | 0.75 | — | — | |
| SCHEMBL12613989 | 0.75 | — | — | |
| SCHEMBL11241636 | 0.75 | GAA (0.52) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL12532310 | 0.73 | GAA (0.50) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL295772 | 0.72 | — | — | |
| SCHEMBL8562716 | 0.72 | SMN1; SMN2 (0.48) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| Malonic Acid Diethyl Ester SCHEMBL28885391 | 0.72 | GAA (0.75) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947290-B | Sulfonamido derivatives of 3, 4-diaryl pyrazoles as protein kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2015-05-27 | — | — | CN | claimed |
| CN-104958294-A | Sulfonamido derivatives of 3, 4-diarylpyrazoles as protein kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2015-10-07 | — | — | CN | disclosed |
| CN-102947290-B | Sulfonamido derivatives of 3, 4-diaryl pyrazoles as protein kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2015-05-27 | — | — | CN | disclosed |