SCHEMBL28014223

SCHEMBL28014223

C=C(C)C.CC(C)COC(=O)CC(=O)OCC(C)C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.65
ALDH1A1 P00352 4/20 0.42
GAA P10253 2/20 0.42
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
PPARG P37231 1/20 0.36
NCOA2 Q15596 1/20 0.36
NCOA1 Q15788 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243431 0.91 TSHR (0.56) TSHRALDH1A1GAAMGAMSI
SCHEMBL27101930 0.89 TSHR (0.57) TSHRALDH1A1GAAMGAMSI
SCHEMBL27964667 0.86 TSHR (0.52) TSHRALDH1A1GAAMGAMSI
SCHEMBL28236036 0.86 TSHR (0.52) TSHRALDH1A1GAAMGAMSI
SCHEMBL30059382 0.84 TSHR (0.50) TSHRALDH1A1GAAMGAMSI
SCHEMBL472554 0.84 TSHR (0.50) TSHRALDH1A1GAAMGAMSI
SCHEMBL28235998 0.84 TSHR (0.50) TSHRALDH1A1GAAMGAMSI
Butane SCHEMBL888582 0.84 TSHR (0.50) TSHRALDH1A1GAAMGAMSI
SCHEMBL5859550 0.84 TSHR (0.50) TSHRALDH1A1GAAMGAMSI
SCHEMBL27964716 0.84 TSHR (0.50) TSHRALDH1A1GAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104640886-B The manufacture method of manufacture method for the ingredient of solid catalyst of olefin polymerization, the catalyst for olefin polymerization and olefin polymerization 东邦钛株式会社 2018-04-27 CN disclosed
CN-104640887-B The manufacture method of manufacture method for the ingredient of solid catalyst of olefin polymerization, the catalyst for olefin polymerization and olefin polymerization 东邦钛株式会社 2017-08-29 CN disclosed
CN-105837714-A METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER 东邦钛株式会社 2016-08-10 CN disclosed
CN-104640887-A Production method for solid catalyst component for polymerizing olefins, catalyst for polymerizing olefins, and production method for polymerized olefins TOHO TITANIUM CO LTD 2015-05-20 CN disclosed
CN-104640886-A PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS TOHO TITANIUM CO LTD 2015-05-20 CN disclosed
CN-104470953-A Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer TOHO TITANIUM CO LTD 2015-03-25 CN disclosed