SCHEMBL28015378

SCHEMBL28015378

O=c1ncc2ccccc2[nH]1.O=c1ncc2ccccc2[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA3 P07451 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA13 Q8N1Q1 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
BRD4 O60885 1/20 0.47
IDO1 P14902 2/20 0.45
HSP90AA1 P07900 1/20 0.45
CDK2 P24941 1/20 0.45
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10417 1.00 CA12 (0.48) CA12CA1CA3CA4CA6
SCHEMBL29371690 1.00 CA12 (0.48) CA12CA1CA3CA4CA6
Ammonia Solution, Strong SCHEMBL28596498 0.98 CA12 (0.47) CA12CA1CA3CA4CA6
Phosphine SCHEMBL29179322 0.98 CA12 (0.47) CA12CA1CA3CA4CA6
SCHEMBL29570997 0.98 CA12 (0.47) CA12CA1CA3CA4CA6
Bromide SCHEMBL5616601 0.98 CA12 (0.47) CA12CA1CA3CA4CA6
SCHEMBL31540593 0.98 CA12 (0.47) CA12CA1CA3CA4CA6
Hydrochloric Acid SCHEMBL10501322 0.98 CA12 (0.47) CA12CA1CA3CA4CA6
SCHEMBL21358065 0.98 CA12 (0.47) CA12CA1CA3CA4CA6
Benzene SCHEMBL29025391 0.98 CA12 (0.47) CA12CA1CA3CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744379-B A kind of quianzolinones and its synthetic method 三峡大学 2017-10-27 CN disclosed
CN-104829543-B A kind of 2 (4 oxoalkyl group) quianzolinones and its synthetic method 三峡大学 2017-08-25 CN disclosed
CN-104829543-A 2-(4-oxoalkyl)quinazolinone compound and synthetic method of same UNIV CHINA THREE GORGES CTGU 2015-08-12 CN disclosed
CN-104744379-A Quinazolinone compound and synthetic method thereof UNIV CHINA THREE GORGES CTGU 2015-07-01 CN disclosed