⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12922604 | 0.76 | — | — | |
| SCHEMBL54558 | 0.71 | — | — | |
| SCHEMBL1746534 | 0.69 | — | — | |
| SCHEMBL4894701 | 0.69 | — | — | |
| SCHEMBL1387866 | 0.69 | — | — | |
| SCHEMBL5896893 | 0.69 | — | — | |
| SCHEMBL1098521 | 0.67 | — | — | |
| SCHEMBL27528957 | 0.67 | — | — | |
| SCHEMBL22042504 | 0.65 | — | — | |
| SCHEMBL4895652 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217358-A1 | INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS OF USING SAME | 1st Biotherapeutics, Inc. (KR) | 2023-08-02 | — | — | EP | claimed |
| US-11649255-B2 | Indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors and methods using same | 1ST Biotherapeutics, Inc. (KR) | 2023-05-16 | — | — | US | claimed |
| CN-114599651-A | Indazoles as inhibitors of hematopoietic progenitor kinase 1(HPK1) and methods of use thereof | 第一生物治疗股份有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-114599653-A | Indazoles as inhibitors of hematopoietic progenitor kinase 1(HPK1) and methods of use thereof | 第一生物治疗股份有限公司 | 2022-06-07 | — | — | CN | claimed |
| US-20220098219-A1 | INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS USING SAME | 1ST Biotherapeutics, Inc. | 2022-03-31 | — | — | US | claimed |
| WO-2022064459-A1 | INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS OF USING SAME | 1ST Biotherapeutics, Inc. (KR) | 2022-03-31 | — | — | WO | claimed |
| WO-2022064458-A1 | INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS OF USING SAME | 1ST Biotherapeutics, Inc. (KR) | 2022-03-31 | — | — | WO | claimed |
| CN-105980386-B | Pyrazolo compounds and uses thereof | 基因泰克公司 | 2021-08-13 | — | — | CN | claimed |
| EP-3846808-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-07-14 | — | — | EP | claimed |
| US-10189838-B2 | Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMAN-LA ROCHE INC. (US) | 2019-01-29 | — | — | US | claimed |
| EP-0385044-A1 | New piperidine derivatives as antihistaminics | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1990-09-05 | — | — | EP | claimed |
| US-4900656-A | STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1990-02-13 | — | — | US | claimed |
| US-4831035-A | Substituted hexahydroarylquinolizines | MERCK & CO., INC. (US) | 1989-05-16 | — | — | US | claimed |
| US-4756995-A | Support, emulsion layer, dye, rhodium desensitizer | FUJI PHOTO FILM CO., LTD. (JP) | 1988-07-12 | — | — | US | claimed |
| US-4337061-A | NITRO DYES IN AQUEOUS SOLUTION | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-06-29 | — | — | US | claimed |
| US-4311478-A | HAIR DYES | L'OREAL (FR) | 1982-01-19 | — | — | US | claimed |
| US-4259261-A | OXIDATION COLOR DYES FOR HAIR | L'OREAL (FR) | 1981-03-31 | — | — | US | claimed |
| US-4200432-A | HAIR DYES | L'OREAL (FR) | 1980-04-29 | — | — | US | claimed |
| US-4184844-A | Storage stable indoaniline and indophenol dye solutions, a process for producing the same and hair dye compositions containing the same | L'OREAL (FR) | 1980-01-22 | — | — | US | claimed |
| US-4125367-A | FOR KERATINIC FIBERS | L'OREAL (FR) | 1978-11-14 | — | — | US | claimed |