Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29251289 | 0.86 | GRM5 (0.52) | GRM5PTGDR2ACHENFE2L2MME | |
| SCHEMBL16457122 | 0.84 | GRM5 (0.43) | GRM5PTGDR2ACHENFE2L2MME | |
| Fluoride SCHEMBL31286347 | 0.83 | GRM5 (0.50) | GRM5PTGDR2ACHENFE2L2MME | |
| Charcoal, Activated SCHEMBL31286314 | 0.83 | GRM5 (0.50) | GRM5PTGDR2ACHENFE2L2MME | |
| SCHEMBL4351361 | 0.78 | — | — | |
| SCHEMBL301745 | 0.77 | GRM5 (0.42) | GRM5PTGDR2ACHENFE2L2MME | |
| SCHEMBL849221 | 0.77 | GRM5 (0.42) | GRM5PTGDR2ACHENFE2L2MME | |
| SCHEMBL28124359 | 0.77 | GRM5 (0.42) | GRM5PTGDR2ACHENFE2L2MME | |
| SCHEMBL8767077 | 0.77 | GRM5 (0.46) | GRM5PTGDR2ACHENFE2L2MME | |
| SCHEMBL28311795 | 0.77 | GRM5 (0.42) | GRM5PTGDR2ACHENFE2L2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063444-A | Azetidinamide derivatives and uses thereof | 广东东阳光药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-118063445-A | Pyrrolidine amide derivatives and use thereof | 广东东阳光药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-111958890-B | Diethynylbenzene tire release agent | 浙江昂扬新材料科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-111958890-A | Diethynylbenzene tire release agent | 浙江昂扬新材料科技有限公司 | 2020-11-20 | — | — | CN | disclosed |
| CN-104672061-A | Preparation method for chiral halogenated aromatic alcohol | UNIV SHANGHAI | 2015-06-03 | — | — | CN | disclosed |