SCHEMBL28016158

SCHEMBL28016158

Clc1ccc2c(Cl)coc2c1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AHR P35869 9/20 0.45
DAO P14920 1/20 0.42
PTPN1 P18031 1/20 0.41
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
TP53 P04637 1/20 0.39
EGFR P00533 1/20 0.37
MCL1 Q07820 1/20 0.37
TTR P02766 1/20 0.36
MAOB P27338 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20274092 0.82 PTPN1 (0.53) AHRPTPN1ALDH1A1MAPTTP53
SCHEMBL2091505 0.78 AHR (0.42) AHRDAOPTPN1ALDH1A1GAA
SCHEMBL18770042 0.78 PTPN1 (0.39) AHRPTPN1ALDH1A1GAAMAPT
SCHEMBL8269304 0.78 MAPT (0.49) PTPN1ALDH1A1GAAMAPTTP53
SCHEMBL32664376 0.78 AHR (0.42) AHRDAOPTPN1ALDH1A1GAA
SCHEMBL2092632 0.78 KCNA3 (0.44) AHRDAOPTPN1ALDH1A1GAA
SCHEMBL23479358 0.74 NPC1 (0.40) ALDH1A1MAPTTP53
SCHEMBL23478525 0.74 PON1 (0.36) PTPN1ALDH1A1GAAMAPT
SCHEMBL20354835 0.74 DAO (0.41) AHRDAOPTPN1ALDH1A1GAA
SCHEMBL24866893 0.74 POLB (0.42) AHRDAOPTPN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107573363-A The azepine dibenzofurans of supplied for electronic application and the electronic device for including azepine dibenzofurans UDC 爱尔兰有限责任公司 2018-01-12 CN disclosed
CN-104662023-B Azadibenzofurans for electron donating applications UDC 爱尔兰有限责任公司 2017-08-18 CN disclosed
CN-104662023-A Azadibenzofurans for electron donating applications BASF SE 2015-05-27 CN disclosed