Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetraethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethylene Glycol SCHEMBL27700022 | 1.00 | KMT2A (0.69) | KMT2AMEN1TSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL27320211 | 0.97 | TSHR (0.67) | KMT2AMEN1TSHRMAPK1THRB | |
| Pentaethylene Glycol SCHEMBL9467222 | 0.90 | KMT2A (0.73) | KMT2AMEN1TSHRMAPK1THRB | |
| Bicarbonate SCHEMBL28537044 | 0.90 | KMT2A (0.73) | KMT2AMEN1TSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL11091011 | 0.90 | KMT2A (0.73) | KMT2AMEN1TSHRMAPK1THRB | |
| Hexaethylene Glycol SCHEMBL9467416 | 0.90 | KMT2A (0.73) | KMT2AMEN1TSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL9467861 | 0.90 | KMT2A (0.73) | KMT2AMEN1TSHRMAPK1THRB | |
| Triethylene Glycol SCHEMBL9468047 | 0.90 | KMT2A (0.73) | KMT2AMEN1TSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL9273841 | 0.87 | TSHR (0.71) | KMT2AMEN1TSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL2512495 | 0.87 | TSHR (0.71) | KMT2AMEN1TSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104714365-A | Photosensitive composition and photoresist | GUANGDONG DANBOND TECHNOLOGY CO LTD | 2015-06-17 | — | — | CN | disclosed |