Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28016581 | 0.88 | KMT2A (0.40) | KMT2AMEN1HSP90AA1SMN1; SMN2LMNA | |
| Bromide SCHEMBL28446860 | 0.85 | MEN1 (0.42) | KMT2AMEN1HSP90AA1SMN1; SMN2FDPS | |
| SCHEMBL30804201 | 0.84 | EGLN3 (0.42) | KMT2AMEN1HSP90AA1SMN1; SMN2FDPS | |
| Hydrochloric Acid SCHEMBL28438402 | 0.82 | EGLN3 (0.44) | KMT2AMEN1HSP90AA1SMN1; SMN2FDPS | |
| SCHEMBL27206398 | 0.81 | MEN1 (0.44) | KMT2AMEN1HSP90AA1SMN1; SMN2FDPS | |
| SCHEMBL15132767 | 0.79 | MEN1 (0.41) | KMT2AMEN1HSP90AA1SMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL21001792 | 0.79 | MEN1 (0.37) | KMT2AMEN1HSP90AA1SMN1; SMN2NPSR1 | |
| SCHEMBL18307196 | 0.78 | MEN1 (0.49) | KMT2AMEN1HSP90AA1SMN1; SMN2LMNA | |
| Bromide SCHEMBL18604059 | 0.78 | MEN1 (0.38) | KMT2AMEN1HSP90AA1SMN1; SMN2NPSR1 | |
| SCHEMBL9885385 | 0.77 | MEN1 (0.41) | KMT2AMEN1HSP90AA1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104587907-A | Integrated device and method for capturing and converting CO2 | BEIJING INST PETROCHEM TECH | 2015-05-06 | — | — | CN | claimed |
| CN-204412215-U | Collecting carbonic anhydride transforms the device of integration | BEIJING INST PETROCHEM TECH | 2015-06-24 | — | — | CN | disclosed |
| CN-104587907-A | Integrated device and method for capturing and converting CO2 | BEIJING INST PETROCHEM TECH | 2015-05-06 | — | — | CN | disclosed |