Carbazole

Carbazole

SCHEMBL28016972

c1ccc(-c2ccc3[nH]c4ccccc4c3c2)cc1.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.61
HSD17B10 Q99714 3/20 0.58
ALDH1A1 P00352 2/20 0.58
GPR3 P46089 1/20 0.58
CDK4 P11802 1/20 0.53
CCND1 P24385 1/20 0.53
KIF11 P52732 5/20 0.52
HPGD P15428 3/20 0.52
KDM4E B2RXH2 2/20 0.52
MEN1 O00255 1/20 0.52
MAPT P10636 1/20 0.52
KMT2A Q03164 1/20 0.52
GABRP O00591 2/20 0.50
GABRD O14764 2/20 0.50
GABRA1 P14867 2/20 0.50
GABRB1 P18505 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA5 P31644 2/20 0.50
GABRA3 P34903 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20234009 1.00 AHR (0.61) AHRHSD17B10ALDH1A1GPR3CDK4
SCHEMBL321006 1.00 AHR (0.61) AHRHSD17B10ALDH1A1GPR3CDK4
SCHEMBL30846841 1.00 AHR (0.61) AHRHSD17B10ALDH1A1GPR3CDK4
SCHEMBL20233957 1.00 AHR (0.61) AHRHSD17B10ALDH1A1GPR3CDK4
SCHEMBL7647500 1.00 AHR (0.61) AHRHSD17B10ALDH1A1GPR3CDK4
SCHEMBL29407417 1.00 AHR (0.61) AHRHSD17B10ALDH1A1GPR3CDK4
SCHEMBL3416446 1.00 AHR (0.61) AHRHSD17B10ALDH1A1GPR3CDK4
SCHEMBL20232146 0.98 AHR (0.59) AHRHSD17B10ALDH1A1GPR3CDK4
SCHEMBL17166808 0.96 AHR (0.57) AHRHSD17B10ALDH1A1GPR3CDK4
SCHEMBL21096036 0.96 AHR (0.57) AHRHSD17B10ALDH1A1GPR3CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104650089-A Fluorene derivative containing carbazole-9-yl group and application thereof BEIJING ETERNAL MATERIAL TECHNOLOGY CO LTD 2015-05-27 CN disclosed