Scutellarein

Scutellarein

SCHEMBL28016997

N.O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(O)c(O)c12

nearest known ligand 0.97

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.97
PTPRS Q13332 5/20 0.97
GABRP O00591 4/20 0.97
GABRD O14764 4/20 0.97
GABRA1 P14867 4/20 0.97
GABRB1 P18505 4/20 0.97
GABRG2 P18507 4/20 0.97
GABRB3 P28472 4/20 0.97
GABRA5 P31644 4/20 0.97
GABRA3 P34903 4/20 0.97
GABRA2 P47869 4/20 0.97
GABRB2 P47870 4/20 0.97
GABRA4 P48169 4/20 0.97
GABRE P78334 4/20 0.97
GABRA6 Q16445 4/20 0.97
GABRG1 Q8N1C3 4/20 0.97
GABRG3 Q99928 4/20 0.97
GABRQ Q9UN88 4/20 0.97
CYP1A1 P04798 3/20 0.97
CYP1B1 Q16678 3/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Scutellarein SCHEMBL142093 0.98 KMT2A (1.00) KMT2APTPRSGABRPGABRDGABRA1
Scutellarein SCHEMBL29004586 0.98 KMT2A (1.00) KMT2APTPRSGABRPGABRDGABRA1
Scutellarein SCHEMBL29692708 0.98 KMT2A (1.00) KMT2APTPRSGABRPGABRDGABRA1
Scutellarein SCHEMBL1900314 0.97 KMT2A (0.97) KMT2APTPRSGABRPGABRDGABRA1
Scutellarein SCHEMBL15241295 0.97 KMT2A (0.97) KMT2APTPRSGABRPGABRDGABRA1
Scutellarein SCHEMBL28230300 0.97 KMT2A (0.97) KMT2APTPRSGABRPGABRDGABRA1
Scutellarein SCHEMBL15090395 0.97 KMT2A (0.97) KMT2APTPRSGABRPGABRDGABRA1
Scutellarein SCHEMBL28045966 0.95 KMT2A (0.94) KMT2APTPRSGABRPGABRDGABRA1
Scutellarein SCHEMBL23854870 0.93 KMT2A (0.89) KMT2APTPRSGABRPGABRDGABRA1
Scutellarein SCHEMBL27890318 0.93 KMT2A (0.89) KMT2APTPRSGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104592184-A Scutellarin aglycone crystal form and preparation method thereof YUNNAN INST MATERIA MEDICA 2015-05-06 CN claimed
CN-107501223-A Scutellarein crystal formation and preparation method thereof 云南省药物研究所 2017-12-22 CN disclosed
CN-104592184-B Scutellarin aglycone crystal form and preparation method thereof 云南省药物研究所 2017-09-29 CN disclosed
CN-104592184-A Scutellarin aglycone crystal form and preparation method thereof YUNNAN INST MATERIA MEDICA 2015-05-06 CN disclosed