Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.68 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833119 | 0.98 | CYP19A1 (0.67) | CYP19A1TPSAB1TPSD1TPSG1KDM4E | |
| SCHEMBL9078420 | 0.85 | CYP19A1 (0.69) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6347647 | 0.84 | CYP19A1 (0.68) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27820726 | 0.83 | CYP19A1 (0.71) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1301606 | 0.83 | CYP19A1 (0.71) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5049441 | 0.81 | CYP19A1 (0.71) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17737185 | 0.81 | CYP19A1 (0.64) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17737149 | 0.81 | CYP19A1 (0.64) | CYP19A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9336424 | 0.81 | CYP19A1 (1.00) | CYP19A1 | |
| SCHEMBL7407605 | 0.79 | CYP19A1 (0.63) | CYP19A1ALDH1A1HPGDCYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492361-B | Substituted 1-benzylcycloalkylcarboxlic acids and use thereof | BAYER IP GMBH | 2015-07-15 | — | — | CN | disclosed |