SCHEMBL28017240

SCHEMBL28017240

C=CC(C)C=CCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
ALDH1A1 P00352 2/20 0.44
PTGS1 P23219 1/20 0.43
PPARG P37231 1/20 0.43
OPRK1 P41145 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 3/20 0.35
GMNN O75496 2/20 0.35
LMNA P02545 2/20 0.35
GLA P06280 2/20 0.35
POLB P06746 2/20 0.35
THRB P10828 2/20 0.35
CETP P11597 2/20 0.35
MAPK1 P28482 2/20 0.35
CXCR5 P32302 2/20 0.35
CCR6 P51684 2/20 0.35
BLM P54132 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8706604 0.86
SCHEMBL16155835 0.79 PTGS1 (0.33) PTGS1PPARGOPRK1ABCG2MEN1
SCHEMBL29083515 0.79 MEN1 (0.52) ALDH1A1MEN1KMT2ACYP3A4MAPT
SCHEMBL9331914 0.79 CNR2 (0.39) MEN1KMT2ACYP3A4MAPTGMNN
SCHEMBL1783382 0.77 TSHR (0.44) TSHRALDH1A1MEN1KMT2ACYP3A4
SCHEMBL1783383 0.77 TSHR (0.44) TSHRALDH1A1MEN1KMT2ACYP3A4
SCHEMBL9208182 0.76
SCHEMBL2122857 0.76
SCHEMBL16287785 0.76
SCHEMBL9208178 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102695690-B Process and system for the production of isoprene LUMMUS TECHNOLOGY INC 2015-05-06 CN disclosed