Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721542 | 0.93 | CA1 (0.50) | CA1CA2ZDHHC7TDP1CHRM1 | |
| SCHEMBL14601911 | 0.88 | CA1 (0.48) | CA1CA2ZDHHC7SMN1; SMN2TSHR | |
| SCHEMBL16626822 | 0.88 | CA1 (0.48) | CA1CA2ZDHHC7SMN1; SMN2TSHR | |
| SCHEMBL26828350 | 0.84 | CA1 (0.48) | CA1CA2ZDHHC7TDP1CHRM1 | |
| SCHEMBL13752800 | 0.84 | CHRM1 (0.44) | CA1CA2ZDHHC7TDP1CHRM1 | |
| SCHEMBL4756217 | 0.84 | CHRM1 (0.44) | CA1CA2ZDHHC7TDP1CHRM1 | |
| SCHEMBL4756212 | 0.84 | CHRM1 (0.44) | CA1CA2ZDHHC7TDP1CHRM1 | |
| SCHEMBL15015726 | 0.84 | CHRM1 (0.44) | CA1CA2ZDHHC7TDP1CHRM1 | |
| SCHEMBL28223548 | 0.84 | ZDHHC7 (0.59) | CA1CA2ZDHHC7ABCB1USP2 | |
| SCHEMBL13752802 | 0.83 | CA1 (0.42) | CA1CA2ZDHHC7TDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041313-A | Pyridine-sulfonamide compounds and their use against pain and related conditions | 基因泰克公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-104860951-A | Modulators of 5-HT receptors and methods of use thereof | AbbVie Deutschland GmbH and Co KG | 2015-08-26 | — | — | CN | disclosed |
| CN-103002735-B | Modulators of 5-ht receptors and methods of use thereof | ABBVI CO | 2015-05-20 | — | — | CN | disclosed |