⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778096 | 0.79 | CA1 (0.42) | — | |
| SCHEMBL776575 | 0.77 | — | — | |
| SCHEMBL4667979 | 0.74 | — | — | |
| SCHEMBL16046532 | 0.74 | CA1 (0.39) | — | |
| SCHEMBL779221 | 0.74 | CA1 (0.39) | — | |
| SCHEMBL24612803 | 0.74 | — | — | |
| SCHEMBL29278630 | 0.74 | — | — | |
| SCHEMBL16045058 | 0.74 | CA1 (0.39) | — | |
| SCHEMBL9344376 | 0.74 | — | — | |
| SCHEMBL964195 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2244710-A1 | A METHOD OF ADMINISTERING A PDE3 INHIBITOR VIA TITRATION FOR THE TREATMENT OF PERIPHERAL ARTERIAL DISEASE | Indigo Pharmaceuticals (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010099388-A1 | COMBINATIONAL USE OF A PDE3 INHIBITOR AND OTHER AGENTS | INDIGO PHARMACEUTICALS (US) | 2010-09-02 | — | — | WO | disclosed |
| WO-2009097406-A1 | A METHOD OF ADMINISTERING A PDE3 INHIBITOR VIA TITRATION FOR THE TREATMENT OF PERIPHERAL ARTERIAL DISEASE | INDIGO PHARMACEUTICALS (US) | 2009-08-06 | — | — | WO | disclosed |
| US-20080200336-A1 | HERBICIDAL COMPOSITION | SYNEGENTA CROP PROTECTION, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-6962894-B1 | comprise a herbicide and a safener (counter-agent, antidote) and protect the useful plants, but not the weeds, against the phytotoxic action of the herbicide | SYNGENTA CROP PROTECTION, INC. (US) | 2005-11-08 | — | — | US | disclosed |
| US-20050164886-A1 | Herbicidal compositions | ALSONS CORPORATION | 2005-07-28 | — | — | US | disclosed |
| EP-1209975-B1 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2003-11-12 | — | — | EP | disclosed |
| EP-1209975-A1 | HERBICIDAL COMPOSITION | Syngenta Participations AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| EP-1157694-A1 | REMEDIAL AGENT FOR ERECTILE DYSFUNCTION | Nissan Chemical Industries, Ltd. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001017353-A1 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |
| EP-0482208-B1 | PYRIDAZINONE DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5318968-A | Antithrombotic agents; cardiotonic agents; vasodilators | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5314883-A | Vasodilation, anticoagulants | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-05-24 | — | — | US | disclosed |
| US-5231101-A | Antihistamines | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-07-27 | — | — | US | disclosed |
| US-5202323-A | Antithrombotic, inotropic, vasodilator, antiallergen | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0495484-A1 | Novel benzo [5,6] cyclohepta [1,2-b] pyridine derivatives and antiallergic agents comprising same | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-07-22 | — | — | EP | disclosed |
| EP-0482208-A1 | PYRIDAZINONE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-04-29 | — | — | EP | disclosed |