Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721714 | 0.77 | CPA1 (0.53) | CPA1TSHRMEN1LMNABLM | |
| SCHEMBL27995707 | 0.76 | CPA1 (0.41) | CPA1TSHRHCAR3 | |
| SCHEMBL2944717 | 0.75 | ACE (0.46) | CPA1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL13040584 | 0.75 | ACE (0.46) | CPA1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL25847046 | 0.75 | ACE (0.46) | CPA1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL12260419 | 0.75 | ACE (0.46) | CPA1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27984989 | 0.75 | ACE (0.46) | CPA1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27995748 | 0.74 | CPA1 (0.40) | CPA1HCAR3 | |
| SCHEMBL22118347 | 0.73 | CPA1 (0.50) | CPA1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL22118346 | 0.73 | CPA1 (0.50) | CPA1SLC1A3SLC1A2SLC1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104703973-A | Substituted phenyl carbamate compounds | HOFFMANN LA ROCHE | 2015-06-10 | — | — | CN | disclosed |