Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28704125 | 0.97 | TSHR (0.47) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL474044 | 0.97 | TSHR (0.47) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL21990266 | 0.95 | TSHR (0.45) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL21990268 | 0.95 | TSHR (0.45) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL27888872 | 0.93 | TSHR (0.43) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28170221 | 0.89 | TSHR (0.39) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28188669 | 0.87 | TSHR (0.38) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL27719118 | 0.87 | TSHR (0.38) | TSHRNAPRTTDP1 | |
| Piperazine SCHEMBL27802271 | 0.87 | TSHR (0.38) | TSHRNAPRTTDP1 | |
| Benzene SCHEMBL487381 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844636-B | High-temperature water thermal synthesis based on pyridine bromide-triazole Cd (II) coordination compound and application | 天津师范大学 | 2016-09-21 | — | — | CN | claimed |
| CN-104844636-A | High-temperature hydrothermal synthesis and application based on bromopyridine-triazole Cd(II) complex | UNIV TIANJIN NORMAL | 2015-08-19 | — | — | CN | claimed |
| CN-104844634-A | Thiocyanic acid radical-controlled bromopyridine-triazole Zn (II) complex high-temperature solvothermal synthesis and application | UNIV TIANJIN NORMAL | 2015-08-19 | — | — | CN | claimed |
| CN-104844568-A | High-temperature solvothermal synthesis and application based on bromopyridine-triazole Zn(II) complex | UNIV TIANJIN NORMAL | 2015-08-19 | — | — | CN | claimed |
| CN-104844636-B | High-temperature water thermal synthesis based on pyridine bromide-triazole Cd (II) coordination compound and application | 天津师范大学 | 2016-09-21 | — | — | CN | disclosed |
| CN-104844636-B | High-temperature water thermal synthesis based on pyridine bromide-triazole Cd (II) coordination compound and application | 天津师范大学 | 2016-09-21 | — | — | CN | disclosed |
| CN-104844636-B | High-temperature water thermal synthesis based on pyridine bromide-triazole Cd (II) coordination compound and application | 天津师范大学 | 2016-09-21 | — | — | CN | disclosed |
| CN-104844636-A | High-temperature hydrothermal synthesis and application based on bromopyridine-triazole Cd(II) complex | UNIV TIANJIN NORMAL | 2015-08-19 | — | — | CN | disclosed |
| CN-104844634-A | Thiocyanic acid radical-controlled bromopyridine-triazole Zn (II) complex high-temperature solvothermal synthesis and application | UNIV TIANJIN NORMAL | 2015-08-19 | — | — | CN | disclosed |
| CN-104844568-A | High-temperature solvothermal synthesis and application based on bromopyridine-triazole Zn(II) complex | UNIV TIANJIN NORMAL | 2015-08-19 | — | — | CN | disclosed |