Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27652150 | 0.78 | HDAC3 (0.60) | BCHEHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL27630590 | 0.76 | HDAC3 (0.62) | BCHEHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL28019641 | 0.76 | BCHE (0.48) | BCHEHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL27742584 | 0.75 | F2 (0.63) | BCHEHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL26331482 | 0.75 | CYP1A2 (0.49) | ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL27810920 | 0.74 | BCHE (0.61) | BCHEHPGDEPHX1RAB9ANPC1 | |
| SCHEMBL28019638 | 0.74 | BCHE (0.55) | BCHEHPGDKCNA3KMT2A | |
| SCHEMBL19641338 | 0.73 | BCHE (0.48) | BCHEHPGDEPHX1ALDH1A1USP2 | |
| SCHEMBL562869 | 0.73 | KCNA3 (0.56) | BCHEHPGDEPHX1ALDH1A1USP2 | |
| SCHEMBL27721872 | 0.73 | BCHE (0.61) | BCHEHPGDEPHX1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640856-A | Carbazole-containing sulfonamides as cryptochrome modulators | RESET THERAPEUTICS INC | 2015-05-20 | — | — | CN | disclosed |