Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16815447 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2PTPRAKMT2AFFAR4CPA1 | |
| SCHEMBL16815699 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2PTPRAKMT2AFFAR4CPA1 | |
| SCHEMBL16861339 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2PTPRAKMT2ACPA1KDM6B | |
| Trifluoroacetic Acid SCHEMBL4598196 | 0.75 | KDM4E (0.36) | SMN1; SMN2FFAR4CPA1CYP2C9CYP2C19 | |
| SCHEMBL7360936 | 0.74 | APOBEC3G (0.55) | FFAR4CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL16815322 | 0.73 | PPARG (0.55) | SMN1; SMN2PTPRAPPARGEPHX2PPARA | |
| SCHEMBL4597973 | 0.71 | CYP1A2 (0.61) | SMN1; SMN2KMT2ACYP2C9CYP1A2 | |
| SCHEMBL16815369 | 0.71 | PPARG (0.49) | SMN1; SMN2PTPRAFFAR4CYP2D6PPARG | |
| SCHEMBL1822200 | 0.71 | PPARG (0.51) | SMN1; SMN2PTPRAKMT2AKDM6BPPARG | |
| SCHEMBL8953481 | 0.71 | PPARG (0.51) | SMN1; SMN2PTPRAKMT2AKDM6BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725397-A | Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-06-24 | — | — | CN | disclosed |