Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.71 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.71 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.71 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.71 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.64 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453351 | 0.90 | NR1H4 (0.73) | MAPTCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL4257510 | 0.88 | NR1H4 (0.76) | MAPTCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL7635847 | 0.88 | NPC1 (0.84) | MAPTCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL14339507 | 0.87 | MAPT (0.77) | MAPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8361566 | 0.87 | MAPT (0.77) | MAPTTP53RXFP1RAB9AKDM4E | |
| Iodide SCHEMBL30758616 | 0.86 | NPC1 (0.82) | MAPTCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL22192246 | 0.86 | SMN1; SMN2 (0.81) | MAPTTP53RAB9AKDM4EALDH1A1 | |
| SCHEMBL4104949 | 0.84 | PPARA (0.68) | MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7294717 | 0.84 | MAPT (0.73) | MAPTRAB9AKDM4EALDH1A1TSHR | |
| SCHEMBL9695914 | 0.84 | MAPT (0.73) | MAPTRAB9AKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104739820-A | Small molecule inhibitor and application thereof to inhibiting ornithine decarboxylase (ODC) | UNIV CHINA THREE GORGES CTGU | 2015-07-01 | — | — | CN | disclosed |