Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101889 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL1428216 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL27639917 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL22021637 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL1521056 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL30883267 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL30122631 | 0.76 | MAPK1 (0.75) | KDM4EALDH1A1L3MBTL1LMNAALOX15 | |
| SCHEMBL1102251 | 0.76 | KDM4E (0.62) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL1682746 | 0.76 | MAPK1 (0.75) | KDM4EALDH1A1L3MBTL1LMNAALOX15 | |
| SCHEMBL8347824 | 0.75 | MEN1 (0.68) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768556-A | Treatment of addiction and impulse control disorders using PDE7 inhibitors | OMEROS CORP | 2015-07-08 | — | — | CN | disclosed |