SCHEMBL28020191

SCHEMBL28020191

COCCOCc1cnccn1.F[B-](F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
CNR2 P34972 1/20 0.33
SYK P43405 3/20 0.33
BIRC5 O15392 1/20 0.32
RIPK2 O43353 1/20 0.32
SP1 P08047 1/20 0.32
ILF3 Q12906 1/20 0.32
PAK1 Q13153 1/20 0.32
GRM5 P41594 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28020192 0.93 KDM4E (0.39) KDM4EGABRA1GABRG2GABRB3GABRA5
SCHEMBL10849584 0.78 CYP2D6 (0.40) KDM4EGABRA1GABRG2GABRB3GABRA5
SCHEMBL570248 0.77
SCHEMBL31415045 0.77
SCHEMBL10616947 0.75 CYP2D6 (0.49) KDM4ESYKALDH1A1HPGDHSD17B10
SCHEMBL11373437 0.74 GRM5 (0.40) KDM4EGABRA1GABRG2GABRB3GABRA5
SCHEMBL11370497 0.74 GRM5 (0.37) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL4266146 0.73 KDM4E (0.42) KDM4EBIRC5RIPK2SP1ILF3
SCHEMBL5569539 0.73 GRM5 (0.36) KDM4EGABRA1GABRG2GABRB3GABRA5
SCHEMBL28020188 0.73 PSMB5 (0.35) KDM4EGABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102952098-B Pyrazine ionic liquid and its preparation method and application Haiyangwang Lighting Technology Co., Ltd. (CN) 2015-08-05 CN disclosed