Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.38 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29205649 | 0.93 | IDO1 (0.50) | IDO1PDE10AACVR2ATGFBR2ALOX5AP | |
| SCHEMBL31339156 | 0.85 | IDO1 (0.43) | IDO1ACVR2ATGFBR2TXNRD1HTR3A | |
| SCHEMBL25274140 | 0.85 | IDO1 (0.43) | IDO1ACVR2ATGFBR2TXNRD1HTR3A | |
| SCHEMBL31266329 | 0.83 | IDO1 (0.45) | IDO1PDE10AMTNR1AMTNR1B | |
| SCHEMBL20103353 | 0.81 | IDO1 (0.48) | IDO1MTNR1AMTNR1B | |
| SCHEMBL2636703 | 0.79 | IDO1 (0.39) | IDO1HTR2AHTR2C | |
| SCHEMBL21573257 | 0.76 | MAP4K4 (0.45) | ALOX5APFEN1KDM4EALDH1A1HPGD | |
| SCHEMBL16815449 | 0.75 | SMN1; SMN2 (0.40) | IDO1ALOX5APFEN1KDM4EALDH1A1 | |
| SCHEMBL19905881 | 0.74 | MAP4K4 (0.44) | KDM4EALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL19905886 | 0.74 | MAP4K4 (0.44) | KDM4EALDH1A1NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725397-A | Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-06-24 | — | — | CN | disclosed |