SCHEMBL28020965

SCHEMBL28020965

CCCCc1ccc(C2CCCC2O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 6/20 0.44
SLC6A3 Q01959 3/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
LMNA P02545 2/20 0.42
HPGD P15428 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TP53 P04637 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ESR1 P03372 2/20 0.40
ADRA2A P08913 2/20 0.40
ADORA3 P0DMS8 2/20 0.40
TACR2 P21452 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
KDM4E B2RXH2 1/20 0.40
SHBG P04278 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10346537 0.84 SPHK1 (0.50) SPHK1SLC6A3CA1CA2HPGD
SCHEMBL10552999 0.74 SPHK1 (0.48) SPHK1SLC6A3LMNAALDH1A1HSD17B10
SCHEMBL10553006 0.74 SPHK1 (0.48) SPHK1SLC6A3LMNAALDH1A1HSD17B10
SCHEMBL11828165 0.73 SPHK1 (0.62) SPHK1LMNA
SCHEMBL4604755 0.73 SLC18A3 (0.49) SLC6A3ALDH1A1SLC6A2SLC6A4CYP3A4
SCHEMBL4604751 0.73 SLC18A3 (0.49) SLC6A3ALDH1A1SLC6A2SLC6A4CYP3A4
SCHEMBL11165604 0.73 SPHK1 (0.61) SPHK1
SCHEMBL25947323 0.73 SPHK1 (0.45) SPHK1SLC6A3CA1CA2LMNA
SCHEMBL28359944 0.72 CNR2 (0.49) SPHK1SLC6A3LMNAHPGDTP53
SCHEMBL25341890 0.70 SLC18A3 (0.49) SLC6A3SLC6A2SLC6A4HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104710283-B Cyclopentanol compound 国际香料和香精公司 2019-06-11 CN disclosed
CN-104710283-A Novel cyclopentanol compounds INT FLAVORS & FRAGRANCES INC 2015-06-17 CN disclosed