Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.62 |
| ▸ | CCR6 | P51684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15228717 | 0.84 | PARP1 (0.55) | PARP1CCR6KDM4EMAPK1TDP1 | |
| SCHEMBL4434197 | 0.80 | MDM2 (0.67) | CCR6TSHRKDM4EMAPK1TDP1 | |
| SCHEMBL1033211 | 0.79 | PARP1 (0.77) | PARP1KDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL29232726 | 0.79 | CCR6 (0.56) | CCR6TSHRKDM4EMAPK1TDP1 | |
| SCHEMBL8946445 | 0.79 | MDM2 (0.68) | CCR6TSHRKDM4EMAPK1TDP1 | |
| SCHEMBL9784691 | 0.79 | KDM4E (0.55) | CCR6TSHRKDM4EMAPK1TDP1 | |
| SCHEMBL27945291 | 0.78 | PARP1 (0.74) | PARP1KDM4ESMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8345086 | 0.78 | CCR6 (0.56) | CCR6TSHRKDM4ECDC25BALDH1A1 | |
| SCHEMBL4131672 | 0.78 | KDM4E (0.54) | CCR6TSHRKDM4EMAPK1TDP1 | |
| SCHEMBL6442515 | 0.77 | PARP1 (1.00) | PARP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876863-A | Fluorescent probe compound and preparation method and application thereof | UNIV BEIJING AGRICULT | 2015-09-02 | — | — | CN | claimed |
| CN-104876863-A | Fluorescent probe compound and preparation method and application thereof | UNIV BEIJING AGRICULT | 2015-09-02 | — | — | CN | disclosed |