SCHEMBL28022162

SCHEMBL28022162

CCCCSCc1ccccc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
HSPA5 P11021 1/20 0.43
HTR1A P08908 1/20 0.43
CA12 O43570 5/20 0.43
CA2 P00918 5/20 0.43
CA9 Q16790 4/20 0.43
KDM4E B2RXH2 2/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
MPO P05164 1/20 0.40
SLC6A4 P31645 1/20 0.40
CYP2D6 P10635 1/20 0.39
HIF1A Q16665 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
TYR P14679 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250181 0.95 TSHR (0.46) TSHRHSPA5HTR1ACA12CA2
SCHEMBL27820040 0.93 TSHR (0.45) TSHRHSPA5HTR1ACA12CA2
SCHEMBL6654522 0.93 TSHR (0.45) TSHRHSPA5HTR1ACA12CA2
SCHEMBL27820087 0.93 TSHR (0.45) TSHRHSPA5HTR1ACA12CA2
SCHEMBL27839571 0.93 TSHR (0.45) TSHRHSPA5HTR1ACA12CA2
SCHEMBL20239386 0.93 TSHR (0.45) TSHRHSPA5HTR1ACA12CA2
SCHEMBL11226794 0.92 TSHR (0.42) TSHRHSPA5HTR1ACA12CA2
SCHEMBL27839591 0.89 HSPA5 (0.46) TSHRHSPA5HTR1ACA12CA2
SCHEMBL9511130 0.80 HSPA5 (0.50) TSHRHSPA5HTR1ACA12CA2
SCHEMBL181464 0.80 TYR (0.45) KDM4EHSD17B10MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107108919-A Degradation material and the packaging manufactured by degradation material 蒙诺苏尔有限公司 2017-08-29 CN disclosed
CN-104736573-B Method for producing (meth)acrylic-modified polybutadiene 日本曹达株式会社 2017-02-22 CN disclosed
CN-104736573-A Method for producing (meth)acrylic-modified polybutadiene NIPPON SODA CO 2015-06-24 CN disclosed