Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.56 |
| ▸ | BCHE | P06276 | 4/20 | 0.56 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11194497 | 0.95 | KCNH2 (0.56) | MAOBBCHEACHEKCNH2CHRM2 | |
| SCHEMBL6947911 | 0.89 | HDAC3 (0.53) | MAOBBCHEACHEKCNH2CHRM2 | |
| SCHEMBL8021687 | 0.87 | TSHR (0.59) | MAOBBCHEACHEKCNH2CHRM2 | |
| SCHEMBL6944690 | 0.87 | HDAC3 (0.54) | MAOBBCHEACHEKCNH2OPRM1 | |
| SCHEMBL12126085 | 0.85 | KCNH2 (0.69) | MAOBBCHEACHEKCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL5108270 | 0.85 | MAPT (0.62) | MAOBBCHEACHEKCNH2CHRM2 | |
| SCHEMBL9704934 | 0.85 | BCHE (0.47) | MAOBBCHEKCNH2CHRM2HTR1A | |
| SCHEMBL9278088 | 0.84 | KCNH2 (0.72) | MAOBBCHEACHEKCNH2CHRM2 | |
| SCHEMBL12126326 | 0.84 | KCNH2 (0.72) | MAOBBCHEACHEKCNH2CHRM2 | |
| SCHEMBL12126534 | 0.84 | KCNH2 (0.72) | MAOBBCHEACHEKCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693211-A | Imidazole derivative as antiviral agent and pharmaceutical application thereof | NANJING MINGDE NEW DRUG RES AND DEV CO LTD | 2015-06-10 | — | — | CN | disclosed |