(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL28022680

C(=Cc1ccccc1)c1ccccc1.O=c1ccc2ccccc2o1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.74
CA9 Q16790 6/20 0.74
CA1 P00915 4/20 0.74
CA2 P00918 3/20 0.74
CA3 P07451 3/20 0.74
CA4 P22748 3/20 0.74
CA7 P43166 3/20 0.74
CA14 Q9ULX7 3/20 0.74
CA5A P35218 2/20 0.74
CA5B Q9Y2D0 2/20 0.74
LMNA P02545 2/20 0.74
CA6 P23280 2/20 0.74
MCL1 Q07820 2/20 0.74
TDP1 Q9NUW8 2/20 0.74
SOST Q9BQB4 1/20 0.74
MTNR1A P48039 2/20 0.60
ACHE P22303 1/20 0.53
PGR P06401 2/20 0.50
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin SCHEMBL1707385 0.90 CA12 (0.65) CA12CA9CA1CA2CA3
Coumarin SCHEMBL1707384 0.90 CA12 (0.65) CA12CA9CA1CA2CA3
Coumarin SCHEMBL19183240 0.88 CA12 (0.95) CA12CA9CA1CA2CA3
SCHEMBL7358531 0.88 CA12 (0.95) CA12CA9CA1CA2CA3
Cinnamic Acid SCHEMBL4394045 0.87 CA9 (0.61) CA12CA9CA1CA2CA3
Cinnamic Acid SCHEMBL4394043 0.87 CA9 (0.61) CA12CA9CA1CA2CA3
Coumarin SCHEMBL21084931 0.87 CA12 (0.56) CA12CA9CA1CA2CA3
Coumarin SCHEMBL25431834 0.86 CA12 (0.91) CA12CA9CA1CA2CA3
Coumarin SCHEMBL29385611 0.86 CA12 (1.00) CA12CA9CA1CA2CA3
Coumarin SCHEMBL1038138 0.86 CA12 (1.00) CA12CA9CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104892556-B One class stilbene coumarin derivatives and preparation method thereof and purposes 合肥工业大学 2017-01-04 CN claimed
CN-104892556-B One class stilbene coumarin derivatives and preparation method thereof and purposes 合肥工业大学 2017-01-04 CN disclosed
CN-104892556-B One class stilbene coumarin derivatives and preparation method thereof and purposes 合肥工业大学 2017-01-04 CN disclosed
CN-104892556-B One class stilbene coumarin derivatives and preparation method thereof and purposes 合肥工业大学 2017-01-04 CN disclosed
CN-104892556-A Stilbene coumarin derivative as well as preparation method and application thereof UNIV HEFEI TECHNOLOGY 2015-09-09 CN disclosed
CN-104892556-A Stilbene coumarin derivative as well as preparation method and application thereof UNIV HEFEI TECHNOLOGY 2015-09-09 CN disclosed