Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963434 | 0.78 | KMT2A (0.43) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL23166469 | 0.76 | MEN1 (0.65) | MEN1KMT2AL3MBTL1OPRM1HTT | |
| SCHEMBL27891808 | 0.74 | IDO1 (0.40) | MEN1KMT2AIDO1TDO2L3MBTL1 | |
| SCHEMBL17754979 | 0.73 | CA1 (0.44) | KMT2AIDO1TDO2L3MBTL1POLB | |
| SCHEMBL8506775 | 0.72 | CCNB2 (0.48) | L3MBTL1HTR1AKDM4EALDH1A1LMNA | |
| SCHEMBL6698808 | 0.71 | ACP3 (0.53) | MEN1KMT2AL3MBTL1HTTNPSR1 | |
| SCHEMBL68782 | 0.71 | HTR2A (0.46) | L3MBTL1HTR2AKDM4ECYP2D6CYP2C19 | |
| SCHEMBL27891817 | 0.71 | TAAR1 (0.42) | MEN1KMT2AIDO1TDO2L3MBTL1 | |
| SCHEMBL28669118 | 0.71 | MEN1 (0.47) | MEN1KMT2AL3MBTL1ATMHTT | |
| SCHEMBL13232511 | 0.70 | APP (0.48) | MEN1KMT2AIDO1TDO2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860803-B | Biphenyl ketonic compound and its preparation method and application | 暨南大学 | 2016-11-30 | — | — | CN | disclosed |
| CN-104860803-A | Biphenyl compound and preparation method and application thereof | UNIV JINAN | 2015-08-26 | — | — | CN | disclosed |