Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20399718 | 1.00 | ACE (0.31) | ACEGRM2GRM3 | |
| SCHEMBL15114474 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL3512916 | 0.80 | GRM2 (0.36) | GRM2GRM3 | |
| SCHEMBL6919995 | 0.80 | GRM2 (0.36) | GRM2GRM3 | |
| SCHEMBL4254372 | 0.80 | GRM2 (0.36) | GRM2GRM3 | |
| SCHEMBL2026722 | 0.78 | — | — | |
| SCHEMBL2023665 | 0.78 | CHRM2 (0.31) | — | |
| SCHEMBL22518862 | 0.78 | CYP2C19 (0.33) | GRM2GRM3 | |
| SCHEMBL22518863 | 0.78 | CYP2C19 (0.33) | GRM2GRM3 | |
| SCHEMBL10215476 | 0.77 | HSD17B10 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104940202-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-104940202-A | Inhibitors of influenza viruses replication | VERTEX PHARMA | 2015-09-30 | — | — | CN | disclosed |
| CN-104922128-A | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA | 2015-09-23 | — | — | CN | disclosed |
| CN-102458408-B | Inhibitors of influenza virus replication | VERTEX PHARMA | 2015-06-03 | — | — | CN | disclosed |