Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SCN1A | P35498 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490069 | 0.91 | CA1 (0.42) | CA1CA2CA9TP53CA12 | |
| SCHEMBL19303377 | 0.81 | — | — | |
| SCHEMBL27565231 | 0.81 | — | — | |
| SCHEMBL1869617 | 0.81 | — | — | |
| SCHEMBL4610879 | 0.79 | — | — | |
| SCHEMBL4610884 | 0.79 | — | — | |
| SCHEMBL15421871 | 0.79 | — | — | |
| SCHEMBL15421872 | 0.77 | — | — | |
| SCHEMBL28191781 | 0.77 | CA1 (0.39) | CA1CA2CA9TP53CA12 | |
| SCHEMBL778096 | 0.77 | CA1 (0.42) | CA1CA2CA9ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829334-B | Uracil nucleotides are like object and its preparation method and application | 江苏豪森药业集团有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-105829334-A | Uracil nucleotide analogs, preparation methods therefor and uses thereof | 江苏豪森药业集团有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-104761604-A | Uridine monophosphate analogue, and preparation method and applications thereof | JIANGSU HANSOH PHARMACEUTICAL | 2015-07-08 | — | — | CN | disclosed |