Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821056 | 0.80 | MME (0.41) | MMEADRB1ADRB3ROCK2ROCK1 | |
| SCHEMBL16458366 | 0.79 | MME (0.48) | MMEADRB1ADRB3 | |
| SCHEMBL28024292 | 0.73 | TDP1 (0.37) | MME | |
| SCHEMBL9934801 | 0.71 | MME (0.43) | MME | |
| SCHEMBL9934788 | 0.71 | MME (0.43) | MME | |
| SCHEMBL27932200 | 0.69 | MME (0.37) | MME | |
| SCHEMBL28023728 | 0.68 | MME (0.39) | MME | |
| SCHEMBL27913955 | 0.67 | MME (0.39) | MME | |
| SCHEMBL27913953 | 0.66 | MME (0.58) | MME | |
| SCHEMBL16458036 | 0.66 | MME (0.51) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261168-B | Enkephalinase inhibitor | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2015-08-05 | — | — | CN | disclosed |