Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17077660 | 0.88 | MAPT (0.60) | MAPTTP53POLBPDE10AMEN1 | |
| SCHEMBL1408408 | 0.87 | MAPT (0.59) | MAPTTP53POLBPDE10AMEN1 | |
| SCHEMBL18355755 | 0.84 | MAPT (0.57) | MAPTTP53POLBPDE10AMEN1 | |
| SCHEMBL14686866 | 0.81 | MAPT (0.59) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL1858815 | 0.80 | HTT (0.58) | MAPTTP53PDE10AGABRPGABRD | |
| SCHEMBL1408015 | 0.80 | MAPT (0.58) | MAPTTP53POLBPDE10AMEN1 | |
| SCHEMBL1408019 | 0.79 | MAPT (0.57) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL29241838 | 0.79 | MAPT (0.67) | MAPTTP53POLBPDE10AMEN1 | |
| SCHEMBL19350703 | 0.79 | PDE10A (0.51) | MAPTTP53POLBPDE10AGABRP | |
| SCHEMBL27728531 | 0.79 | PDE10A (0.51) | MAPTTP53POLBPDE10AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971291-B | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2015-07-22 | — | — | CN | disclosed |