Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.72 |
| ▸ | PPARA | Q07869 | 3/20 | 0.72 |
| ▸ | PPARD | Q03181 | 1/20 | 0.72 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.66 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784440 | 0.87 | SOAT1 (0.81) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL17471275 | 0.86 | PPARG (0.85) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL6744450 | 0.86 | PPARG (0.76) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL10587602 | 0.85 | SOAT1 (0.86) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL9257327 | 0.85 | SOAT1 (0.86) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL6747512 | 0.85 | PPARG (0.73) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL9152529 | 0.84 | SOAT1 (0.67) | PPARGPPARAPPARDSOAT1SOAT2 | |
| Gsk-9578 SCHEMBL68327 | 0.84 | PPARG (1.00) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL8159724 | 0.84 | PPARA (1.00) | PPARGPPARAPPARDSOAT1SOAT2 | |
| Gsk-9578 SCHEMBL30475595 | 0.84 | PPARG (1.00) | PPARGPPARAPPARDSOAT1SOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103687856-B | A novel 1,2,3,4-tetrahydroquinoline derivative useful for the treatment of diabetes | LILLY CO ELI | 2015-07-22 | — | — | CN | disclosed |