Benzene

Benzene

SCHEMBL28024147

O=S(=O)(O)c1ccc2[nH]c3ccccc3c2c1.c1ccccc1

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 2/20 0.56
CDK5R1 Q15078 2/20 0.56
GSK3B P49841 1/20 0.56
AHR P35869 1/20 0.52
PTPN11 Q06124 7/20 0.50
KIF11 P52732 1/20 0.49
ALDH1A1 P00352 2/20 0.48
GPR3 P46089 1/20 0.48
HSD17B10 Q99714 1/20 0.48
F2 P00734 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
HPGD P15428 1/20 0.48
PTGS1 P23219 1/20 0.48
KDR P35968 1/20 0.48
BLM P54132 1/20 0.48
WRN Q14191 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CDK4 P11802 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9225081 0.98 CDK1 (0.57) CDK1CDK5R1GSK3BAHRPTPN11
SCHEMBL9221704 0.97 CDK1 (0.56) CDK1CDK5R1GSK3BAHRPTPN11
SCHEMBL3267890 0.89 PTPN11 (0.54) CDK1CDK5R1GSK3BPTPN11ALDH1A1
SCHEMBL29534191 0.89 PTPN11 (0.54) CDK1CDK5R1GSK3BPTPN11ALDH1A1
SCHEMBL29106657 0.87 GAA (0.61) CDK1CDK5R1GSK3BPTPN11ALDH1A1
SCHEMBL31351281 0.84 GAA (0.58) CDK1CDK5R1GSK3BAHRPTPN11
SCHEMBL14980276 0.84 GAA (0.58) CDK1CDK5R1GSK3BAHRPTPN11
SCHEMBL31544362 0.81 AHR (0.53) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL9221701 0.81 AHR (0.53) AHRKIF11ALDH1A1GPR3HSD17B10
SCHEMBL28190463 0.81 BRAF (0.65) AHRKIF11ALDH1A1GPR3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104803817-A Method for synthesizing arenesulphonate compound UNIV SHANGHAI 2015-07-29 CN disclosed