SCHEMBL28024162

SCHEMBL28024162

Nc1ccc(O)c2ncccc12.[Co]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 5/20 0.96
IDO1 P14902 3/20 0.96
HSP90AB1 P08238 2/20 0.96
PSMB5 P28074 1/20 0.96
KDM4E B2RXH2 9/20 0.59
L3MBTL1 Q9Y468 5/20 0.59
LMNA P02545 3/20 0.59
HTT P42858 3/20 0.59
MAPT P10636 3/20 0.59
BRD4 O60885 2/20 0.59
METAP2 P50579 2/20 0.59
MPI P34949 1/20 0.59
METAP1 P53582 1/20 0.59
SLC6A2 P23975 1/20 0.59
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
GAA P10253 1/20 0.58
FTO Q9C0B1 2/20 0.57
NPSR1 Q6W5P4 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL688655 0.98 HSP90AA1 (1.00) HSP90AA1IDO1HSP90AB1PSMB5KDM4E
SCHEMBL29721839 0.98 HSP90AA1 (1.00) HSP90AA1IDO1HSP90AB1PSMB5KDM4E
Bromide SCHEMBL7118628 0.96 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5KDM4E
SCHEMBL31441082 0.96 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5KDM4E
Hydrochloric Acid SCHEMBL29845219 0.96 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5KDM4E
SCHEMBL31441084 0.96 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5KDM4E
Hydrochloric Acid SCHEMBL361071 0.96 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5KDM4E
Hydrochloric Acid SCHEMBL3682081 0.96 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5KDM4E
Hydrochloric Acid SCHEMBL4457813 0.96 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5KDM4E
Hydrochloric Acid SCHEMBL27468026 0.96 HSP90AA1 (0.96) HSP90AA1IDO1HSP90AB1PSMB5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104830313-B Preparation method of {[Co(5-amino-8-hydroxyquinoline)2].H2O}n complex with blue light property 吉林化工学院 2017-01-11 CN disclosed
CN-104830313-A Preparation method of {[Co(5-amino-8-hydroxyquinoline)2].H2O}n complex with blue light property JILIN INST CHEMICAL TECHNOLOGY 2015-08-12 CN disclosed