Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.67 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.66 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.58 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15847352 | 0.88 | MAPT (0.74) | MAPTKCNK3KCNK9P2RX1LMNA | |
| SCHEMBL4286068 | 0.87 | MAPT (0.94) | MAPTKCNK3KCNK9P2RX1LMNA | |
| SCHEMBL15847043 | 0.83 | KCNK3 (0.92) | MAPTKCNK3KCNK9P2RX1LMNA | |
| SCHEMBL4683413 | 0.83 | KCNK3 (0.88) | MAPTKCNK3KCNK9P2RX1LMNA | |
| SCHEMBL17052860 | 0.83 | MAPT (0.70) | MAPTKCNK3KCNK9P2RX1LMNA | |
| SCHEMBL24141032 | 0.82 | MAPT (0.84) | MAPTKCNK3KCNK9P2RX1LMNA | |
| SCHEMBL5335860 | 0.82 | KMT2A (0.62) | MAPTKCNK3KCNK9LMNAMEN1 | |
| SCHEMBL15847037 | 0.82 | MAPT (0.64) | MAPTKCNK3KCNK9P2RX1LMNA | |
| SCHEMBL2493221 | 0.82 | MAPT (0.88) | MAPTKCNK3KCNK9P2RX1LMNA | |
| SCHEMBL826721 | 0.82 | MAPT (0.83) | MAPTKCNK3KCNK9P2RX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143209-A | Biaryl amide compounds as kinase inhibitors | NOVARTIS AG | 2015-12-09 | — | — | CN | disclosed |