Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27595539 | 0.82 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27487740 | 0.81 | TDP1 (0.48) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27744083 | 0.81 | TDP1 (0.48) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28314994 | 0.81 | TDP1 (0.48) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28133014 | 0.80 | TDP1 (0.46) | TDP1 | |
| SCHEMBL1769190 | 0.79 | — | — | |
| Tert-Butyl Formate SCHEMBL27698101 | 0.79 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27698140 | 0.79 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28039293 | 0.79 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28017814 | 0.79 | TDP1 (0.45) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918940-B | Purine inhibitors of human phosphatidylinositol 3-kinase | 默沙东公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-104918940-A | Purine inhibitors of human phosphatidylinositol 3-kinase | MERCK SHARP & DOHME | 2015-09-16 | — | — | CN | disclosed |